#262: Holly Ahern, PhD – How to Properly Test for Lyme

In this episode you will learn three main things:

  1. The dangers of using doxycycline as an antibiotic.
  2. The time limit before Lyme Disease becomes chronic.
  3. The best tests for diagnosing different types of tick borne infections.

Guest Bio:

Holly Ahern is an associate professor of microbiology at SUNY Adirondack who runs an undergraduate research lab. When Holly Ahern found out several years ago that her daughter’s mysterious illness was Lyme disease, she quickly immersed herself in the subject.

Dr. Ahern has become an advocate for developing a broader understanding of Lyme disease – one aimed at treating the chronic symptoms commonly reported by patients who were misdiagnosed or received inadequate treatment in the disease’s early stages.

Lyme Action Network:

lymeactionnetwork.org

Lyme Action Network

LymeDisease.org:

lymedisease.org

Lyme Disease dot Org

 

4 comments on “#262: Holly Ahern, PhD – How to Properly Test for Lyme

  1. Cheyenne Lang says:

    Please cite the reference to John Flab’s research on doxycycline making the Lyme spirochete go into persister cells. I can’t find it anywhere on the internet. That statement is very important.

    1. lymeninja says:

      I contacted Dr. Ahern and this is what she replied.

      Below is the article I was referring to – I don’t know who John Flab is – this is research from Zhang’s lab at JHU. Amoxicillin is used to “induce” persister Bb’s to form, and when the amoxicillin-induced persisters are treated with doxycycline, 83% of the persister cells survive the treatment.

      https://www.ncbi.nlm.nih.gov/pubmed/26014929
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876775/
      http://www.discoverymedicine.com/Jie-Feng/2019/03/persister-biofilm-microcolony-borrelia-burgdorferi-causes-severe-lyme-arthritis-in-mouse-model/

  2. lymeninja says:

    Also from Dr. Ahern

    And – this article directly references doxycycline driving Bb into the persister state.

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482230/

    From the Abstract:

    Recent studies have shown that Borrelia burgdorferi can form antibiotic-tolerant persisters in the presence of microbiostatic drugs such as doxycycline.

    1. Cheyenne Lang says:

      Thank you so very much for getting me these articles LymeNinja and Holly Ahern. Your efforts are very much appreciated. You’re the best!

      (Too funny that I heard John Flab for Zang’s Lab.)

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